August 1, 2013

3 Min Read
Survey Implicates Feed as Possible Cause of PEDV

An epidemiological survey tracking the cause of spread of porcine epidemic diarrhea (PED) virus has implicated feed as a strong possibility, according to preliminary data released by USDA’s Center for Epidemiology and Animal Health (CEAH) and reported by the American Association of Swine Veterinarians (AASV).

Survey data were collected by AASV veterinarians associated with swine herds affected by PED virus. Veterinarians were requested to complete questionnaires for case and control herds. Control herd data were proposed to be matched with case herds on certain characteristics. The final data was submitted to USDA’s CEAH through a link created by the National Center for Foreign Animal and Zoonotic Disease Defense at Texas A&M. CEAH conducted the following analysis. Data on the full population affected by the outbreak were not available, so an evaluation of the representativeness of the sample is not possible.

A herd was considered a case based on a fecal sample confirmed positive for PED virus via fecal polymerase chain reaction (PCR).

Seven feed-related variables were associated with higher odds of PED virus (“risk factors”):

  • Using sow feed that was custom mixed off-farm in the last 90 days;

  • How many meal/mash rations were fed to nursery or finishers in the last 90 days;

  • The total number of different rations fed to finisher pigs in the 90 days prior to the administration of the questionnaire;

  • The contents in terms of supplementation that was in the premix for the most recent finisher diet; and

  • What type of grain mix was used for sow or finisher feed in the past 90 days.


Although data were collected on companies that supplied supplement, base mix and premix, none of the companies were associated with being a case farm during preliminary analysis.

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Several variables were associated with lower odds of PED virus (“protective factors”):

  1. Higher swine farm density in a three-mile radius;

  2. The percent of replacement animals that came from the same state as the farm surveyed;

  3. Vaccination of breeding females for ileitis or porcine circovirus-associated type 2 in the previous six months;

  4. The three-month average mortality in the nursery unit;

  5. Vaccination of weaned market pigs for salmonella in the previous six months; and

  6. Number of pelleted rations fed to sows.


Due to the limited sample size, it is unlikely that any of these risk factors point directly to the source of the PED virus outbreak, the AASV report indicates.

However, a number of feed practices may be indicators of risk. The origin of sow feed as well as the type, premix contents and number of different rations fed to weaned market pigs in the last 90 days increases the odds of being a case as much as three and a half times. Use of a “grain mixed with amino acid source and a base mix” was associated with an increased risk of PED virus for both sow feed and finisher feed. This type of grain mix may warrant further investigation as a possible source of PED virus. However, increasing the number of pelleted rations fed to sows appears to have a protective effect, and the reason for this is unclear.

Barring contamination, vaccinating sows or weaned market pigs for specific agents is unlikely to cause a decrease in the odds of PED virus. It could be that vaccination is a signal indicating higher health herds with higher biosecurity and less chance for pathogen entry.

Additionally, odds ratios approaching one, such as farm density and percent of new entries, can be ignored despite significance.

You might also like:

Porcine Epidemic Diarrhea (PED) Virus: FAQ and Survival Tips

Evaluating Energy in Swine Diets



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