National Hog Farmer is part of the Informa Markets Division of Informa PLC

This site is operated by a business or businesses owned by Informa PLC and all copyright resides with them. Informa PLC's registered office is 5 Howick Place, London SW1P 1WG. Registered in England and Wales. Number 8860726.

National Hog Farmer

BACTOCELL®: the First Probiotic Authorized for use in Aquaculture in the European Union

Lallemand’s unique lactic acid bacteria recognized to improve performance in salmonids and shrimp

Milwaukee - Lallemand Animal Nutrition is pleased to announce that the European Standing Committee on Animal Nutrition[1] has voted for the authorization of its probiotic, Bactocell® (lactic acid bacteria strain Pediococcus acidilactici CNCM MA18/5M), for use as a zootechnical feed additive in salmonids and shrimp. Bactocell therefore becomes the first probiotic authorized for such use in aquaculture in the European Union. This authorization is based on the recognition of the quality and safety (QPS status) as well as the efficacy of Bactocell in beneficially enhancing salmonid and shrimp production.

In salmonids, Bactocell is able to improve the quality of the final fish products by increasing the number of well-conformed fish (prevention of Vertebral Compression Syndrome). This syndrome, which is thought to affect over 20% of rainbow trout harvested constitutes an important economic loss for fish farmers. The use of Bactocell® in the prevention of Vertebral Compression Syndrome in salmonids is the subject of an international patent filed by IFREMER and INRA in 2006.

In shrimp, Bactocell is able to increase survival and growth performance. The trials submitted with the application dossier unequivocally demonstrated beneficial effects in terms of growth enhancement, feed utilization, as well as improved resistance against Vibrio sp. infections.

Today, pressure for both sustainable and profitable aquaculture has fuelled the search for acceptable solutions for optimizing production in a natural and environmentally friendly way. Probiotics, which are defined as “live-microorganisms which, when administered in adequate amounts, confer a health benefit on the host”, have been empirically linked to improvements in aquaculture production in certain regions. However, until now, the use of micro-organisms for zootechnical improvements in aquaculture had not been unequivocally demonstrated nor authorized in the European Union. This therefore appears to be the first of such authorization in Europe.

Probiotics in animal nutrition are classified in Europe as zootechnical feed additives, and as such are subject to very strict scientific assessments, requirements and Regulations. Their assessments, by a panel of scientific experts, include in-depth evaluation of the identity, composition, quality, safety and efficacy of the particular strain on the intended target species. It is therefore a lengthy process demanding important investments by the manufacturer.

The exploratory trials on the possible use of Bactocell® in aquaculture started in 2002, with first, feasibility trials on live preys (Gatesoupe, 2002). This was followed by numerous field trials and in-depth studies, on shrimp, salmonids and other marine fishes, some of which will be subject to EU authorization following steeply from this first. The application dossiers for the use of Bactocell in shrimp and salmonids are therefore the fruit of several years of intellectual investment as well as, research and development conducted in close partnership with renowned researchers, institutions and leading private companies in aquaculture.

Bactocell® (Pediococcus acidilactici MA18/5M) is already authorized (since 2005) for use as a zootechnical feed additive in fattening pigs and chickens. Lallemand has recently sought to expand the use of this specific strain to cover permanent use in layers and piglets.


About LallemandLallemand, Inc. is a privately owned Canadian company specialized in yeast, bacteria and yeast derivatives, for animal nutrition, baking, winemaking and pharmaceutical industries. Lallemand is the only major supplier of yeast and bacteria that is a primary producer of both.

Lallemand Animal Nutrition is dedicated to the development, production, and marketing of profitable, natural and differentiated solutions for animal nutrition and health. Our core products are live bacteria for probiotics and silage inoculants, specific yeast for probiotics, and high value yeast derivatives.

Lallemand is a major supplier of probiotics and silage inoculants in Europe, North America and Africa. We also have a growing presence in Asia and South America. More news from Lallemand Animal Nutrition can be seen on