When it comes to treating disease on your operation, isolating the source can be difficult. That’s why protecting the entire population with Denagard^® is the proactive choice that’s right for your herd and best for your business.

Denagard and chlortetracycline (CTC) control swine dysentery associated with Brachyspira hyodysenteriae susceptible to tiamulin, treats swine bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis sensitive to CTC, and treats bacterial pneumonia caused by Pasteurella multocida sensitive to CTC.

Denagard and CTC both act at the ribosomal level, inhibiting protein synthesis, but their binding sites are different. Together, the two antibiotics increase the activity against labeled pathogens and enlarge the spectrum of control to certain gram-negative bacteria. While using Denagard alone does not require a Veterinary Feed Directive (VFD), using Denagard + CTC does.

Study - Effects of two Denagard + CTC pulses in grow-finish pigs¹
To understand the effects of Denagard + CTC in grow-finish pigs, a commercial population of approximately 1,150 growing pigs averaging approximately 75 lb with a known history of swine pneumonia and bacterial enteritis was used. Confirmation of the disease-causing bacterial agents (Pasteurella multocida, Escherichia coli, and Salmonella choleraesuis)  was determined using laboratory diagnostics.

Treatment groups
Treatment 1 was the control group, with no medication provided. The pigs in Treatment 2 were given Denagard at 35 grams/ton + 400 grams/ton CTC from days 7 to 20 and days 49 to 62.

Key findings

Incidence of disease for pens treated with Denagard + CTC was numerically lower than in the control group.  Additionally, the need to treat diarrhea and lameness with antibiotics was reduced for those in the Denagard + CTC group.

As a result of controlling and treating disease, pens treated with Denagard + CTC performed better overall than the control group with:

●       Heavier final weights — 314.3 lb vs. 310.8 lb

●       Better average daily gain (ADG) — 2.24 lb vs. 2.21 lb

●       Improved average daily feed intake (ADFI) — 6.30 lb vs. 6.18 lb

Are you doing what’s right for your herd and best for your business?

Talk to your local Elanco sales representative or technical consultant to learn more about protecting whole-herd health with Denagard.

The label contains complete use information, including cautions and warnings. Always read, understand and follow the label and use directions.

Denagard^® LC
INDICATIONS:

For treatment of swine dysentery associated with Brachyspira hyodysenteriae susceptible to tiamulin:

For treatment of swine pneumonia associated with Actinobacillus pleuropneumoniae susceptible to tiamulin:

IMPORTANT SAFETY INFORMATION

Denagard 10 Premix
INDICATIONS:

For control of swine dysentery associated with Brachyspira hyodysenteriae susceptible to tiamulin:

For treatment of swine dysentery associated with Brachyspira hyodysenteriae susceptible to tiamulin:

For control of ileitis associated with Lawsonia intracellularis susceptible to tiamulin:

IMPORTANT SAFETY INFORMATION

Denagard + CTC
INDICATIONS:

For the control of swine dysentery associated with Brachyspira hyodysenteriae susceptible to tiamulin and for treatment of swine bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis sensitive to chlortetracycline and treatment of bacterial pneumonia caused by Pasteurella multocida sensitive to chlortetracycline:

Using Denagard alone does not require a Veterinary Feed Directive (VFD). Using Denagard + CTC does require a VFD.

CAUTION: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

IMPORTANT SAFETY INFORMATION

¹Elanco Animal Health. Data on file.

Denagard and Elanco are trademarks of Elanco or its affiliates.
© 2018 Elanco or its affiliates.
Elanco supports the use of shared class antibiotics for therapeutic uses while under the oversight of a veterinarian. More details on Elanco’s Antibiotic, Welfare and Sustainability Policies can be found on https://www.elanco.com/our-responsibilty#responsible-use-of-antibiotics.
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