While swine pneumonia and bacterial enteritis may be subclinical at times, they still limit pig performance and profitability. As production moves into the fall and winter months, subclinical diseases may become clinical with increased stress due to environmental changes.

“During times of transition, when labeled pathogens are present, it’s more effective for producers to take a proactive approach by using an in-feed antibiotic than it is to have to scramble and treat a disease that has already gained a foothold,” says Dr. Kevin Eggers, DVM, Elanco Animal Health.

The combination of Denagard^® 10 premix + CTC (chlortetracycline):

“Together, Denagard and CTC target on-label pathogens, inhibiting protein synthesis, by working at the ribosomal level,” explains Eggers. “But because their binding sites are different, the two modes of action have a larger spectrum of control over certain gram-negative bacteria when fed separately or individually.”

To demonstrate the efficacy of different antibiotic feeding programs, a study was conducted using a commercial population of approximately 2,250 nursery pigs with a known history of swine pneumonia and bacterial enteritis.¹

Confirmation of the disease-causing bacterial agents (Pasteurella multocida and Escherichia coli) was determined via laboratory diagnostics. The table below provides additional information about typical symptoms associated with these diseases.

The study included three treatments:

Live performance from start to day 14: 30-pen study

By treating Escherichia coli and Pasteurella multocida, Denagard + CTC improves:

“The study found that by treating pneumonia and enteritis caused by Pasteurella multocida and Escherichia coli, pigs that received in-feed antibiotics had restored appetites and improved growth,” says Eggers. “A healthier pig is obviously better equipped to handle the disease challenges that come with the changing seasons.”

The labels contain complete use information, including cautions and warnings. Always read, understand and follow the label and use directions.

INDICATIONS: DENAGARD 10 PREMIX

For control of swine dysentery associated with Brachyspira hyodysenteriae susceptible to tiamulin:

For treatment of swine dysentery associated with Brachyspira hyodysenteriae susceptible to tiamulin:

For control of ileitis associated with Lawsonia intracellularis susceptible to tiamulin:

INDICATIONS: DENAGARD + CTC

For the control of swine dysentery associated with Brachyspira hyodysenteriae susceptible to tiamulin and for treatment of swine bacterial enteritis caused by Escherichia coli and Salmonella choleraesuis sensitive to chlortetracycline and treatment of bacterial pneumonia caused by Pasteurella multocida sensitive to chlortetracycline:

Using Denagard alone does not require a Veterinary Feed Directive (VFD). Using Denagard + CTC does require a VFD.

CAUTION: Federal law restricts medicated feed containing this veterinary feed directive (VFD) drug to use by or on the order of a licensed veterinarian.

IMPORTANT SAFETY INFORMATION

INDICATIONS: DENAGARD LC

For treatment of swine dysentery associated with Brachyspira hyodysenteriae susceptible to tiamulin:

For treatment of swine pneumonia associated with Actinobacillus pleuropneumoniae susceptible to tiamulin:

IMPORTANT SAFETY INFORMATION

**INDICATIONS: MECADOX AND TERRAMYCIN^®

¹Elanco Animal Health. Data on file.
²Zimmerman, J., Karriker, L. et al. (2012). Pasteurellosis. Diseases of Swine. 10: 803, 806.
³Zimmerman, J., Karriker, L. et al. (2012). Bacterial diseases. Diseases of Swine. 10: 826-829.
⁴Zimmerman, J., Karriker, L. et al. (2012). Bacterial diseases. Diseases of Swine. 10: 728-739.

Denagard, Elanco and the diagonal bar are trademarks of Eli Lilly and Company or its affiliates.
© 2017 Eli Lilly and Company or its affiliates.

All other products are the property of their respective owners.
Elanco supports the use of shared class antibiotics for therapeutic uses while under the oversight of a veterinarian. More details on Elanco’s Antibiotic, Welfare and Sustainability Policies can be found on www.elanco.com/antimicrobialpolicy.